Trinity is Ireland’s leading university and is ranked 75th in the world (QS World University Rankings 2026). Founded in 1592, the University is steeped in history with a reputation for excellence in education, research, and innovation, which has been inspiring generations of thinkers for over 400 years. Trinity College Dublin- an introduction.

The Ryan Lab investigates how pathogenic mitochondrial DNA mutations influence innate immune function, inflammatory responses, and susceptibility to infection. This role will initially focus on ex vivo macrophage biology, using primary mouse macrophages derived from mitochondrial disease models to understand how distinct mtDNA mutations alter innate immune signalling, inflammatory cytokine production, cellular metabolism, and responses to immune or infectious stimuli.

The postholder will contribute to a programme of work integrating macrophage wet-lab experiments with mouse models of mitochondrial disease, downstream immunology, metabolism, and molecular biology workflows. The role is intended to provide broad practical and intellectual training in mitochondrial immunometabolism and would be particularly suited to a motivated candidate seeking further research experience before undertaking a PhD.

Applicants should submit a full Curriculum Vitae plus a short cover letter outline the candidate’s relevant laboratory experience, interest in the research area, and motivation for applying for the role and include the names and contact details of 2 referees (including email addresses), to:-

Dr. Dylan Ryan

ryand67@tcd.ie

They are key to the success of our Strategic Plan. We centre our behavioural values around the importance of belonging. We recognise that the university will thrive by each of us respecting and caring for one another. We know we can achieve much more through working together. We know too that we must take responsibility for our actions and be accountable. We must, and will never stop, imagining. And through being nature positive we connect not just with the environment but with our ambitions for a sustainable future.

At Trinity, we are committed to equality, diversity, and inclusion. We welcome applications from all individuals, including those with disabilities, those who have followed non-traditional career paths, and those who have taken time out for reasons such as family or caring responsibilities. We also welcome international applicants, including those who have been displaced due to conflict or war.

Trinity College Dublin is Ireland’s premier university. We are an EU Sustainable Gender Equality Champion and hold an Athena Swan Silver Award, recognising our ongoing work to advance gender equality both within Trinity and across the higher education sector. Trinity is committed to supporting work–life balance and creating a family-friendly working environment.