You will be interviewed several times. The first one will be by the phone. You won't call them, they will call you. The first interview will be a background. If they like you, they will refer you to a store.
The second interview will be from an employee, usually from HR or management. They can be lenient to prospective employees, and will also ask about your background, and a few questions based on situations, and a 'What Would You Do' kind of fashion. Nothing to fret about, just a mild q&a.
The third interview will be from the Store Manager. The Store Manager can be a wild card, so be prepared. Sometimes, they can be polite and relaxed, like mine was. Other times, according to other associates from other stores, they can be hell bent and a tad bit over abrasive with a short temper tantrum equivalent to that of a spoiled child. They don't last long at one store, though. They will ask you about why you want to work at The Home Depot, so do your research thoroughly! Don't forget to show enthusiasm and cheerfulness.