Pros
well-respected institution with interesting work and good upper management. Benefits and pay are also competitive. You can see an impact from your work in coverage of its reports.
Cons
One issue: middle management is uneven-some managers are very ineffective and difficult to work with. This partly a personal issue, with certain managers undermining employees and disregarding input or opinions. It's also a professional issue, with poor project management and unclear guidance leading to chaotic work flows. A bigger issue is that there are few internal mechanisms to address this-review of managers doesn't include all direct reports, there are no dispute resolution mechanisms, etc. So if you're stuck with a bad manager there's not much to do but leave. Another is that there is a clear hierarchy among projects, and if you end up on of the lower-priority projects you can quickly become marginalized with little opportunity to move into a different area.